73 Results for "

Euphorbia helioscopia L.

" in MedChemExpress (MCE) Product Catalog:
Products (73)

73 Results for "Euphorbia helioscopia L." in MCE Product Catalog:

11
Resiniferatoxin
Resiniferatoxin
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11 Publications Verification
Cat. No.: HY-N2333
CAS No.: 57444-62-9
Synonyms: (+)-Resiniferatoxin
Category:  

Cardiovascular Disease Euphorbia resinifera O. Berg Monophenols Phenols Euphorbiaceae Plants Disease Research Fields

Target:  

TRP Channel

Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period .
5
Ingenol Mebutate
Ingenol Mebutate
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5 Cited Publications
Cat. No.: HY-B0719
CAS No.: 75567-37-2
Synonyms: Ingenol 3-angelate; PEP005
Category:  

Terpenoids Euphorbia peplus Linn. Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

PKC

Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
5
20-Deoxyingenol
20-Deoxyingenol
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5 Cited Publications
Cat. No.: HY-N0866
CAS No.: 54706-99-9
Category:  

Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Autophagy

20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA) .
1
Jolkinolide B
Jolkinolide B
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1 Cited Publications
Cat. No.: HY-N0732
CAS No.: 37905-08-1
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants Disease Research Fields Cancer

Target:  

IAP Akt Caspase NF-κB TGF-beta/Smad JAK Bacterial Apoptosis

Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
Euphol
Euphol
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Cat. No.: HY-N0313
CAS No.: 514-47-6
Category:  

Triterpenes Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

MAGL Endogenous Metabolite

Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
Euphorbia Factor L2
Euphorbia Factor L2
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Cat. No.: HY-N5001
CAS No.: 218916-51-9
Category:  

Gramineae Terpenoids Leptochloa chinensis (Linn.) Nees Diterpenoids Plants Disease Research Fields Cancer

Target:  

Apoptosis

Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway .
Tirucallol
Tirucallol
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Cat. No.: HY-N2556
CAS No.: 514-46-5
Category:  

Triterpenes Euphorbia boetica Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .
5,15-Diacetyl-3-benzoyllathyrol
5,15-Diacetyl-3-benzoyllathyrol
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Cat. No.: HY-N0562
CAS No.: 218916-52-0
Synonyms: Euphorbia factor L3
Category:  

Gramineae Terpenoids Leptochloa chinensis (Linn.) Nees Diterpenoids Plants Disease Research Fields Cancer

Target:  

Others

5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.
Euphornin
Euphornin
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Cat. No.: HY-N11774
CAS No.: 80454-47-3
Category:  

Natural Products Euphorbia helioscopia L. Euphorbiaceae Plants

Target:  

Apoptosis Caspase

Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein .
Euphoscopin B
Euphoscopin B
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Cat. No.: HY-N12730
CAS No.: 81557-52-0
Category:  

Terpenoids Euphorbia helioscopia L. Euphorbiaceae Diterpenoids Plants

Target:  

Others

Euphoscopin B (compound 5) is a cytotoxic macrocyclic diterpene isolated from Euphorbia helioscopia L .
Ingenol-3-palmitate
Ingenol-3-palmitate
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Cat. No.: HY-137242
CAS No.: 52557-26-3
Purity:  99.65%
Category:  

Terpenoids Euphorbiaceae Diterpenoids Plants Euphorbia kansuensis Prokh.

Target:  

HIV

Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC50 value of 4.1 nM .
3,3'-Di-O-methylellagic acid
3,3'-Di-O-methylellagic acid
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Cat. No.: HY-N1969
CAS No.: 2239-88-5
Synonyms: 3,8-Di-O-methylellagic acid
Category:  

Euphorbia adenochlora Plants Infection Combretaceae Ketones, Aldehydes, Acids Phenols Polyphenols Euphorbiaceae Terminalia chebula Retz. Disease Research Fields

Target:  

Bacterial

3,3'-Di-O-methylellagic acid obtained from Euphorbia adenochlora selectively inhibits the formation of acid-fastness in mycobacteria without retardation of their growth. 3,3'-di-O-methylellagic acid as a hepatoprotective compound is apparently due to its antioxidative effect .
Candelilla wax
Candelilla wax
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Cat. No.: HY-W123056
CAS No.: 8006-44-8
Synonyms: Euphorbia CERIFERA (CANDELILLA) WAX
Candelilla wax is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
31-Norlanostenol
31-Norlanostenol
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Cat. No.: HY-N7267
CAS No.: 16910-39-7
Category:  

Triterpenes Euphorbia boetica Terpenoids Euphorbiaceae Plants Disease Research Fields Endocrinology

Target:  

Others

31-Norlanostenol is a triterpenic compound isolated from the latex of Euphorbia officinarum. 31-Norlanostenol can act as efficient insect growth regulator on S. frugiperda and Tenebrio molitor .
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one
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Cat. No.: HY-N8560
CAS No.: 244277-75-6
Category:  

Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Euphorbiaceae Diterpenoids Plants

Target:  

Others

3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one is a Diterpenoids product that can be isolated from the roots of Euphorbia kansui. .
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate
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Cat. No.: HY-N10990
CAS No.: 944799-47-7
Category:  

Terpenoids Euphorbiaceae Diterpenoids Plants Euphorbia officinarum (Hook.f. et Coss.) Vindt

Target:  

Others

Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate is a highly functionalized ingol diterpene that can be isolated from Euphorbia officinarum latex .
Fischeria A
Fischeria A
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Cat. No.: HY-133209
CAS No.: 221456-63-9
Category:  

Terpenoids Euphorbiaceae Diterpenoids Plants Euphorbia kansuensis Prokh.

Target:  

Others

Fischeria A is a norditerpene lactone of a new carbon skeleton, can be isolated from Euphorbia fischeriana .
Jolkinolide A
Jolkinolide A
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Cat. No.: HY-119767
CAS No.: 37905-07-0
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants

Target:  

VEGFR Apoptosis

Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells .
Euphol (Standard)
Euphol (Standard)
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Cat. No.: HY-N0313R
CAS No.: 514-47-6
Category:  

Triterpenes Terpenoids Euphorbiaceae Plants

Target:  

MAGL Endogenous Metabolite Reference Standards

Euphol (Standard) is the analytical standard of Euphol. This product is intended for research and analytical applications. Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
Euphorbia factor L7b
Euphorbia factor L7b
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Cat. No.: HY-N8118
CAS No.: 93550-95-9
Category:  

other families Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields

Target:  

Others

Euphorbia factor L7b is an isolathyrolditerpene compound .
Assay Types